How to Choose Quality Supplements

“I took them. I didn’t notice any difference.”

We hear this from people all the time in their first appointment, and almost always they say it with a trace of guilt — as if they’d done something wrong, or as if their body simply doesn’t respond the way it’s supposed to.

Most of the time neither is true. The bottle had the right name on it, but the actual amount per dose was far smaller than it looked. Or the recommended dose was three capsules and you were taking one. Or, quite often, the supplement was fine and simply wasn’t needed.

This article won’t tell you what to buy. It’ll show you how to judge it yourself. By the end you’ll be able to turn a bottle around and, within a minute, have a much clearer picture of what you’re actually buying.

You don’t need to memorize anything. You just need to know where to look.

Transparency note. Further down you’ll find a link to Welldium, where you get 15% off. Panagiotis Tsintavis has a commercial partnership with them, which means he may benefit if you buy through it. We’d rather you knew that before reading our recommendation. The criteria below are the same ones we use for products he earns nothing from.

In this article:

Serving size — how many capsules? Amount per serving “Other ingredients” — the excipients The real information is on the label

The question we all skip

Before every “which one,” there’s an “if.”

The most common way of thinking about supplements is simple and convenient: I have this symptom, so there must be something that fixes it. Tired, so iron. Not sleeping, so magnesium. Bloated, so probiotics.

It doesn’t work that way, and we see it clearly every time someone arrives with a bag full of bottles. The symptom doesn’t tell you where it came from. The same fatigue can be connected to iron, to the thyroid, to sleep, to the gut — or to three of those at once.

So a supplement makes sense when there’s one of the following: a documented deficiency, an increased need at this stage of your life, or a specific, defined reason with a time frame. Without one of those, even the best product on the market is mostly an expense.

Related: how we approach a case, and why we don’t work from a “this supplement for that condition” model.

Why two identical bottles aren’t identical

Take two bottles of omega-3. Both say “1000 mg” on the front.

That number describes the fish oil. It doesn’t tell you how much EPA and DHA is in there, and that’s where the two products can differ considerably. If one delivers half the amount of the other, you need twice the capsules to get the same amount of EPA and DHA — which means the cheaper bottle can be the more expensive one.

“1000 mg” “1000 mg” EPA + DHA EPA + DHA one capsule two capsules for the same

You’ll see the same pattern in plenty of other supplement categories. The number that impresses isn’t always the number that answers your question.

So we don’t compare two products on what the front of the bottle says. We go to the supplement facts panel, find the amount per serving, and check how many capsules that serving is.

Ten minutes at the kitchen table

Before you buy anything else, it’s worth doing this first. It’s free, and it’s usually the most profitable ten minutes of the whole exercise.

Take out everything you’re currently taking and put it all on the table. For each one:

  1. Turn the bottle around. The information that matters is on the back.
  2. Find the serving size. How many capsules do the numbers on the label refer to? And how many are you taking?
  3. Find the amount of the ingredient per serving — not just the large number on the front.
  4. Look at the form, not only the name. You’ll usually find it next to the ingredient name or in the label panel.
  5. Go down to “other ingredients” at the end of the label.
  6. Ask why you started it — and whether that reason still applies.
Very often, when we do this exercise together, we find things that have no reason to continue. Not because they’re dangerous — because they don’t deliver what you thought they did, or because the reason you started them has passed. That’s a gain, not a loss. The money you don’t spend on supplements you don’t need is available for something that has a real reason to be in your plan.

The six things we look at

1. Amount of the ingredient per serving

The first thing we look for, and it isn’t necessarily the large number on the front of the pack. Alongside it we always check the serving size. If one product delivers that amount in four capsules and another in one, it changes both the practicality and the real cost of daily use.

2. Form

Most vitamins and minerals exist in more than one form. They differ mainly in solubility, absorption, and how well the gut tolerates them — and those three aren’t the same for everyone. You’ll usually find the form next to the ingredient name or in the label panel.

3. Which dose you need, and for how long

If the dose is too low for the particular goal, it may simply not be enough. On the other hand, more doesn’t automatically mean better — a number of vitamins and minerals interact with each other in absorption and metabolism. Higher doses can have their place, but in a specific context and usually for a defined period.

4. Excipients

The “other ingredients” at the end of the label. Some excipients are needed for manufacturing, stability, or delivery. Others may be added for practical reasons such as improving shelf life or making production easier. If you tend to react to many supplements, this is one more part of the label worth checking before assuming the nutrient itself is the problem.

More: the ingredients you don’t want in your supplements, and why you might react to almost everything.

5. Quality control

Look for transparent quality control processes and, where available, independent certification or an accessible certificate of analysis.

Check what each mark actually certifies, though, because they don’t all mean the same thing. GMP concerns the manufacturing process and isn’t the same as independent testing of the finished product. And verification programs each check different things — ingredient identity, declared amount, contaminant limits — without being a guarantee of effectiveness.

6. Value, not price

The more expensive option isn’t automatically the better one. The right question isn’t what the bottle costs, but what the daily dose you actually need costs. A bottle at half the price that requires three times the capsules is the more expensive one.

What changes by category

If you take Look at What actually matters
B complex / multivitamin forms and actual amounts per serving not just a “high potency” claim
Magnesium form and magnesium per serving how much magnesium the serving really delivers, and in how many capsules
Omega-3 EPA and DHA separately not the “1000 mg fish oil”
Vitamin D form and amount per serving the dose isn’t chosen blind
Iron form and iron per serving we wouldn’t start it without a clear indication
Probiotics strains and storage conditions not just the billions of CFU

A little more detail on five categories where the label most often causes confusion.

Magnesium. The forms differ mainly in solubility, absorption, and how well the gut tolerates them. Some have a more pronounced laxative effect than others, and that alone determines whether you’ll be able to take it consistently. So the choice depends on the goal and on how you personally tolerate it.

Omega-3. We look first at how much EPA and DHA the daily serving delivers and how many capsules that takes. We also look for quality testing for oxidation and contaminants, because the freshness of the oil matters and isn’t visible from the outside.

Vitamin D. The right dose isn’t the same for everyone — it depends on your levels and on why you’re using it. Levels are assessed mainly through 25-OH-D. It’s absorbed better when taken with a meal containing fat, which matters more than the time of day.

Iron. Here the label is the second question. The first is whether there’s a clear reason to take it, because iron isn’t something we’d use casually when it isn’t needed. When there is one, we look at the form — they differ noticeably in how well the stomach tolerates them — and the amount of iron per serving.

Probiotics. The species name alone isn’t always enough. In many cases the evidence relates to specific strains, so we also look at the strain code after the name. We look at how it needs to be stored, too. And we don’t choose a probiotic based only on the billions of CFU printed on the front.

What we’re using at the moment

You can apply the criteria above to any supplement. If you’d also like to see what we’re using at the moment, we keep an updated list on Welldium of the supplements and brands we use or recommend in practice.

The list changes when something changes — when a product isn’t available, or when we find an option we prefer.

You get 15% off through this link.
See what we’re using on Welldium

Four label tricks

The proprietary blend. It gives the total weight of the blend, not how much of each ingredient is in it. In practice, you can’t know what you’re buying.

The serving that isn’t one capsule. The panel gives its numbers per serving, and that serving can be three or four capsules. It’s worth checking that line first, before you compare two products.

The showcase ingredient. An impressive ingredient appears on the front of the pack, but when you look at the label its amount may be very small. So it isn’t enough for an ingredient to be in the product — how much is actually in there matters too.

“Natural” and “clean.” These words tell you very little about the form, the amount, or the quality control behind a supplement. When we see terms like these, we still go back to the label: form, amount, serving size, and quality control.

How you’ll know if it worked

Not every supplement is judged by whether you “felt something.”

Depending on why you’re using it, the response might show up in symptoms, in specific lab markers, or against a goal you set at the start for a defined period of time.

That’s why the question “how will I know if it worked?” is best answered before you start, not three months later. If you don’t know what you’ll look at to judge it, you have no way of deciding when to stop it either.

Frequently asked questions

How do I quickly tell whether a supplement is worth it?

Turn the bottle around and look at three things in this order: the serving size, the amount of the ingredient per serving, and the form next to the name. Those three give you a very good first picture. The full check also includes the excipients, the quality control, and the cost per daily dose.

Are more expensive supplements better?

Not necessarily. There are expensive products that use forms we wouldn’t necessarily choose, and more affordable products that meet all the criteria we’re looking for. The right question isn’t what the bottle costs, but what the daily dose you actually need costs.

What does “serving size” mean on a supplement label?

It’s the amount of product — one, two, or three capsules, for example — that the numbers in the panel refer to. If you don’t check it, you may be comparing two products that in reality deliver very different amounts.

What are excipients, and should I worry about them?

They’re the “other ingredients” at the end of the label — everything apart from the active ingredient. Some are needed for manufacturing, stability, or delivery. If you tend to react to many supplements, it’s worth checking them before assuming the nutrient itself is the problem.

What is a proprietary blend?

A mix of ingredients declared by its total weight, without stating how much of each is included. In practice it means you can’t tell whether the ingredient you care about is present in a meaningful amount or only symbolically.

Do I actually need supplements?

It depends. A supplement makes sense when there’s a documented deficiency, an increased need at this stage of your life, or a specific, defined reason with a time frame. Without one of those, even an excellent product is mostly an expense.

In closing

Reading a label isn’t specialist knowledge. It’s six things, in order, and after three or four bottles it becomes automatic.

Many of the people who come to us have already spent a considerable amount on supplements. That’s why, before we add anything new, we want to look first at what’s already in the cupboard and whether it still has a reason to be there.

Very often, the first gain isn’t something you buy. It’s something you realize you don’t need to buy again.

The next question

Finding a good product is only part of the decision. The more personal part starts after: whether you need it at all, at what dose, for how long, and how you’ll know whether it made a difference for you.

Book a 15-minute Health Strategy Call and we’ll look at where it makes sense to start.